New cancer cachexia model

1 New cancer cachexia rat model generated by implantation of a peritoneal 1 dissemination-derived human stomach cancer cell line 2 3 Kiyoshi Terawaki, Yumi Sawada, Yohei Kashiwase, Hirofumi Hashimoto, Mitsuhiro 4 Yoshimura, Masami Suzuki, Kanako Miyano, Yuka Sudo, Seiji Shiraishi, Yoshikazu Higami, 5 Kazuyoshi Yanagihara, Yoichi Ueta, and Yasuhito Uezono 6 Division of Cancer Pathophysiology, National Cancer Center Research Institute, 5-1-1 Tsukiji, 7 Chuo-ku, Tokyo 104-0045, Japan 8 Division of Translational Research, Exploratory Oncology Research & Clinical Trial Center, 9 National Cancer Center Hospital East, Kashiwa 277-8577, Japan 10 Laboratory of Molecular Pathology and Metabolic Disease, Faculty of Pharmaceutical Sciences, 11 Tokyo University of Science, 2641 Yamazaki, Noda, Chiba 278-8510, Japan 12 Department of Physiology, School of Medicine, University of Occupational and Environmental 13 Health, Kitakyushu 807-8555, Japan 14 Tsumura Research Laboratories, Tsumura & Co., 3586 Yoshiwara, Ami-machi, Inashiki-gun, 15 Ibaraki 300-1192, Japan 16 17 Running head: New cancer cachexia model 18 19 Corresponding Author: 20 Kiyoshi Terawaki, Ph.D. 21 Division of Cancer Pathophysiology 22 National Cancer Center Research Institute 23 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045, Japan 24 E-mail: [email protected] 25 Phone: +81-3-3542-2511, ext. 4453 26 Articles in PresS. Am J Physiol Endocrinol Metab (December 17, 2013). doi:10.1152/ajpendo.00116.2013